Τrypanosoma equiperdum is a protozoan parasite that causes Dourine or covering sickness in horses and other animals in the family equidae. Dourine is a unique disease in the sense that it has no known vectors or fomites existing in the natural world, other tan members of the equine family, including donkeys, mules, and horses. This parasite efficiently evades the host animal’s immune system through the use of variable surface glycoproteins or VSGs. These VSGs allow the organism to constantly manipulate and change the surface structure of its proteins, which means it is constantly being presented to the immune system as a new foreign organism and this prevents the body from mounting a large enough immune response to eradicate the disease.
End-Point | MANUAL | MSDS |
One-Step | MANUAL | MSDS |