M.cynos play a role in canine infectious respiratory disease (CIRD), a multifactorial disease involving both viral and bacterial agents. Symptoms of CIRD include a dry cough (often called kennel cough), anorexia, vomiting, and depression. Outbreaks of CIRD are particularly common in kennels. M. cynos has been isolated from dogs with pneumonia and was particularly abundant in the most necrotic areas of the lung.
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