Organoids have emerged as one of the most powerful in vitro models for studying tissue development, regeneration, and disease. Yet their complex three-dimensional structure makes them challenging to visualize and quantify effectively. A live event on November 25, 2025 will explore how multiscale imaging workflows—combining fixed-sample and live microscopy—can overcome these challenges and deliver deeper biological insight.
This webinar brings together leading experts who will share practical strategies for capturing high-quality organoid data across scales.
Event Speakers
- Dr. Gustavo Quintas Glasner de Medeiros
Staff Scientist, Professorship for Multicellular Systems, ETH Zürich - Andrea Boni
Business Excellence Director, Leica Microsystems
Together, they will present state-of-the-art methodologies for integrating multiple imaging modalities into a cohesive organoid analysis pipeline.
What You Will Learn
1. Extracting and Interpreting Multiscale Data
Learn how to analyze datasets that span from whole-organoid morphology to fine cellular structures. The session will highlight strategies to map biological behavior across size scales for meaningful interpretation.
2. Generating Statistically Robust Organoid Datasets
High-content imaging allows researchers to quantify organoid phenotypes across large sample numbers. You’ll discover methods that ensure reproducibility, consistency, and statistical power.
3. Long-Term Live Imaging with Light-Sheet Microscopy
Light-sheet microscopy has become essential for capturing dynamic processes inside 3D biological systems. The webinar will offer insights into:
- maintaining organoid viability over extended imaging sessions
- reducing phototoxicity
- optimizing sample preparation for live volumetric workflows
4. The Role of Open-Source Tools in Standardizing Organoid Imaging
Reproducibility is a major challenge in organoid research. The speakers will discuss collaborative, open-source software tools that support standardized analysis and consistent data handling across laboratories.
Why Multiscale Imaging Matters for Organoid Research
Organoids exhibit complex morphology and dynamic behaviors that cannot be fully captured by a single imaging technique. Fixed-sample high-content imaging provides broad statistical coverage, while live imaging reveals the real-time cellular mechanisms that drive organoid growth and differentiation.
By integrating both modalities, researchers can:
- build comprehensive phenotypic landscapes
- correlate structural features with functional activity
- better understand developmental trajectories
- identify subtle disease-related alterations
This multiscale approach supports more robust conclusions and accelerates discovery across regenerative medicine, oncology, and developmental biology.
Spotlight: Viventis Deep – Leica’s Dual-View Light-Sheet Microscope
The session will also introduce the Viventis Deep, an open-top dual-view light-sheet microscope developed by Leica Microsystems. Key features include:
- long-term live imaging stability
- high-quality volumetric data acquisition
- minimal photobleaching and phototoxicity
- compatibility with large and complex 3D samples
This technology is designed specifically for multicellular systems and organoid research, enabling deeper insight into real-time developmental processes.
Join the Event
Date: November 25, 2025
Time: 4:00 PM (London)
Format: Live Online Webinar
This event is ideal for researchers working in organoid biology, developmental biology, regenerative medicine, and advanced imaging workflows.
Attendees will leave with a complete roadmap for building reproducible, multiscale imaging pipelines and extracting meaningful biological insights from organoid models.