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📅 Published in Tuesday, October 28 of 2025

Meet Lunaphore at the SITC Annual Meeting — Booth #603
📅 November 5–9, 2025
📍 National Harbor, Maryland

Amplify discovery. Accelerate insights.

Join Lunaphore at the Society for Immunotherapy of Cancer (SITC) Annual Meeting 2025 to explore how cutting-edge spatial biology technologies are transforming immuno-oncology research. Through live demos, poster presentations, and data showcases, Lunaphore will present new ways to decode the tumor microenvironment with unprecedented precision.


Revealing spatial insights with COMET™

At the heart of Lunaphore’s presentation is COMET™, the fully automated spatial biology platform that enables simultaneous detection of RNA and protein markers within the same tissue section—at true subcellular resolution.

This unique multiomics approach provides comprehensive insights into the tumor microenvironment (TME), from discovery to translational research.

With the integration of the SPYRE™ Amplification Kit, detection of low-abundance biomarkers becomes possible, expanding access to clinically relevant targets that were previously undetectable.

Complementing this innovation, the SPYRE™ portfolio now includes new modular panels that simplify biomarker discovery and accelerate translational workflows across tumor, stromal, and vascular biology.


Spatial biology in clinical impact: the SECOMBIT trial

Lunaphore’s commitment to advancing precision oncology extends into real-world clinical applications.
The SECOMBIT trial is leveraging COMET™ to investigate the spatial dynamics of the TME and identify patterns predictive of immunotherapy response in melanoma patients.

By integrating advanced spatial proteomics with AI-powered image analysis, this study provides groundbreaking insight into why certain patients respond to treatment while others do not—a vital step toward more effective, personalized cancer therapy.

Experience COMET™ live

Booth #603 | November 7–8

Stop by the Lunaphore booth for a 2-minute walkthrough of the COMET™ platform and an exclusive look at raw multiplex imaging datasets across multiple cancer tissue types.
Meet the team, explore real data, and see how leading laboratories, biopharma, and CROs are using COMET™ to accelerate discovery and translational success.


Poster presentations at SITC 2025

November 7 – Multiomics discovery sessions

  • Fully automated multiomics assay for co-detection of protein–protein interactions, RNA, and protein markers on the same tissue section.
  • Evaluating anti-PD-L1 treatment response in bladder cancer using spatial detection of PD-1/PD-L1 interactions.
  • Comprehensive spatial multiomics mapping across diverse cancer types.
  • Multiomics spatial mapping revealing the tumor microenvironment in fresh frozen samples.

November 8 – Translational and clinical insights

  • A novel multiplex imaging immunotherapy panel with AI-powered spatial biomarker identification in melanoma patients.
  • Multiomics image analysis-driven insights into tumor microenvironment remodeling.
  • Spatial multi-omics mapping revealing tumor plasticity and immune suppression in non-small cell lung cancer.

Pushing the boundaries of immuno-oncology

By merging automation, spatial proteomics, and AI, Lunaphore is redefining how researchers visualize the cellular architecture of cancer—and how clinicians interpret it for treatment.

From poster data to live demonstrations, SITC 2025 offers a first-hand view of how spatial biology is bridging discovery and precision medicine.

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