Equine Protozoal Myeloencephalitis (EPM) is an infection of the central nervous system that can affect equines of any age and sex. EPM is one of the most challenging and exasperating diseases in horses, not only for veterinary scientists but for horse owners as well. The primary parasite that causes the disease is the single-celled protozoan parasite Sarcocystis neurona. The clinical signs of EPM are a result of direct neuronal damage early in the disease and the secondary inflammatory reaction.
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